人表皮T细胞趋化因子|Human CTACK (CCL27)

Synonyms :

Cuteaneous T-cell Attracting Chemokine, CCL27, ALP, Skinkine, Eskine

Description :

CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T-cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant human CTACK is a 10.2 kDa protein containing 88 amino acid residues.

Catalog #:

300-54

Source :

E.coli

Stability :

The lyophilized protein is stable for at least 2 years from date of receipt at -20⁰C. Reconstituted CTACK is stable for at least 3 months when stored in working aliquots with a carrier protein at -20⁰C. Avoid repeated freeze/thaw cycles.

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by its ability to chemoattract CXCR3 transfected cells using a concentration of 10.0-100.0 ng/ml.

Selected References :

Selected List of References Citing This PeproTech Product

AA Sequence :

FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG

PubMed Link :

eskine+AND+human+OR+CTACK+AND+human

Country of Origin :

USA