产品名称:人生长因子-AB|Human PDGF-AB
产品规格:
单 位:瓶
关 键 字:Human PDGF-AB|人生长因子-AB|Human PDGFCANSPEC品质提供的人生长因子-AB|Human PDGF-AB性能**,英文名称人生长因子-AB|Human PDGF-AB,简称为人生长因子-AB|Human PDGF-AB,中文名称为人生长因子-AB|Human PDGF-AB。
产品Human PDGF-AB以其优良的品质满足您不同实验的多种需求。并保证每批人生长因子-AB|Human PDGF-AB的质量和人生长因子-AB|Human PDGF-AB品质优良。English Information
Synonyms :
Platelet-Derived Growth Factor-AB, Glioma-derived growth factor (GDGF), Osteosarcoma-derived Growth Factor (ODGF), PCGF
Description :
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-AB is a 25.5 kDa disulfide-linked dimer, consisting of one A chain and one B chains (234 total amino acids).
Catalog #:
100-00AB
Source :
E.coli
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted PDGF-AB is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 1 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Selected References :
Selected List of References Citing This PeproTech Product
AA Sequence :
alpha chain MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT
beta chain MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIGIVR KKPIFKKATV TLGDHLACKC ETVAAARPVT
PubMed Link :
PDGF-AB
Country of Origin :
USA
国内免费服务专线:400 608 7598(据说天才可以在15秒内记住我们的免费电话哦^_^)
服务升级,全新企业QQ为您服务,企业QQ号:4006087598
创赛官网升级为创赛优选商城,请移步www.canspec.cn注册登录,新用户注册送1000元现金券
沪公网安备 31011402005168号