产品名称：人β防御素-3|Human BD-3|peprotech
产品规格：
单 位：支
关 键 字：人β防御素-3|Human BD-3|peprotech
CANSPEC品质提供的人β防御素-3|Human BD-3|peprotech性能**，英文名称人β防御素-3|Human BD-3|peprotech，中文名称为人β防御素-3|Human BD-3|peprotech。
产品人β防御素-3|Human BD-3|peprotech以其优良的品质满足您不同实验的多种需求。并保证每批人β防御素-3|Human BD-3|peprotech的质量和品质优良。English Information
Synonyms :
beta-defensin-3
Description :
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, four human β-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. Recombinant Human BD-3 is a 5.1 kDa protein containing 45 amino acid residues.
Catalog #:
300-52
Source :
E.coli
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted BD-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater then 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :
Exhibits antimicrobial activity against gram-positive bacteria S. aureus and gram-negative P. aeruginosa and E.coli.
Selected References :
Selected List of References Citing This PeproTech Product
AA Sequence :
GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
PubMed Link :
beta-defensin-3+AND+human
Country of Origin :
USA
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