产品名称：人防御素NP-1|Human NP-1
产品规格：
单 位：支
关 键 字：人防御素NP-1|Human NP-1
CANSPEC品质提供的 人防御素NP-1|Human NP-1性能**，英文名称人防御素NP-1|Human NP-1，中文名称为人防御素NP-1|Human NP-1。
产品人防御素NP-1|Human NP-1以其优良的品质满足您不同实验的多种需求。并保证每批人防御素NP-1|Human NP-1的质量和品质优良。English Information
Synonyms :
Neutrophil Peptide-1, alpha Defensin-1, HNP-1, Cryptdin
Description :
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins which include NP-1, NP-2 and NP-3, are distinguished from the β-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human NP-1 is a 3.4 kDa protein containing 30 amino acid residues.
Catalog #:
300-42
Source :
E.coli
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted NP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :
Determined by its ability to chemoattract immature dendritic cells using a concentration of 1.0-10.0 ng/ml.
Selected References :
Selected List of References Citing This PeproTech Product
AA Sequence :
ACYCRIPACI AGERRYGYCI YQGRLWAFCC
PubMed Link :
NP-1+AND+human+AND+defensin
Country of Origin :
USA
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