产品名称：人肿瘤坏死因子-β|Human TNF-beta (insect cell derived)
产品规格：
单 位：支
关 键 字：人肿瘤坏死因子-β|Human TNF-beta (insect cell derived)
CANSPEC品质提供的 人肿瘤坏死因子-β|Human TNF-beta (insect cell derived)性能**，英文名称人肿瘤坏死因子-β|Human TNF-beta (insect cell derived)，中文名称为人肿瘤坏死因子-β|Human TNF-beta (insect cell derived)。
产品 人肿瘤坏死因子-β|Human TNF-beta (insect cell derived) 以其优良的品质满足您不同实验的多种需求。并保证每批人肿瘤坏死因子-β|Human TNF-beta (insect cell derived) 的质量和品质优良。English InformationSynonyms :Tumor Necrosis Factor-beta, TNFSF1, Lymphotoxin-alpha (LT-alpha)Description :TNF-β is a potent mediator of inflammatory and immune responses. It belongs to the TNF superfamily of ligands and signals through TNFR1 and TNFR2. TNF-β is produced by activated T and B lymphocytes, and has similar activities to TNF-α. Like TNF-α, TNF-β is involved in the regulation of various biological processes incuding cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-β is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-β, which effectively anchors the TNF-β to the cell surface. TNF-β is cytotoxic to a wide range of tumor cells. Recombinant human TNF-β is a secreted 172 amino acid protein (18.6 kDa) which forms an active non-disulfide linked homotrimer structure in solution. Due to glycosylation, TNF-β has an approximate MW of 19.3 kDa based on SDS-PAGE gel amd Mass Spectrometry.* Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.Catalog #:300-01BHSource :(BTI-Tn-5B1-4) High-5 Insect Cells*Stability :The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted TNF-β is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.Purity :Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin Level :Endotoxin level is less than 0.1 ng per µg (1EU/µg).Biological Activity :The ED50 was determined by the cytolysis of murine L929 cells in the presence of actinomycin D is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.AA Sequence :GVGLTPSAAQ TARQHPKMHL AHSTLKPAAH LIGDPSKQNS LLWRANTDRA FLQDGFSLSN NSLLVPTSGI YFVYSQVVFS GKAYSPKATS SPLYLAHEVQ LFSSQYPFHV PLLSSQKMVY PGLQEPWLHS MYHGAAFQLT QGDQLSTHTD GIPHLVLSPS TVFFGAFAL PubMed Link :TNFbeta+AND+humanCountry of Origin :USA
Synonyms :
Tumor Necrosis Factor-beta, TNFSF1, Lymphotoxin-alpha (LT-alpha)
Description :
TNF-β is a potent mediator of inflammatory and immune responses. It belongs to the TNF superfamily of ligands and signals through TNFR1 and TNFR2. TNF-β is produced by activated T and B lymphocytes, and has similar activities to TNF-α. Like TNF-α, TNF-β is involved in the regulation of various biological processes incuding cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-β is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-β, which effectively anchors the TNF-β to the cell surface. TNF-β is cytotoxic to a wide range of tumor cells. Recombinant human TNF-β is a secreted 172 amino acid protein (18.6 kDa) which forms an active non-disulfide linked homotrimer structure in solution. Due to glycosylation, TNF-β has an approximate MW of 19.3 kDa based on SDS-PAGE gel amd Mass Spectrometry.* Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
Catalog #:
300-01BH
Source :
(BTI-Tn-5B1-4) High-5 Insect Cells*
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted TNF-β is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :
The ED50 was determined by the cytolysis of murine L929 cells in the presence of actinomycin D is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
AA Sequence :
GVGLTPSAAQ TARQHPKMHL AHSTLKPAAH LIGDPSKQNS LLWRANTDRA FLQDGFSLSN NSLLVPTSGI YFVYSQVVFS GKAYSPKATS SPLYLAHEVQ LFSSQYPFHV PLLSSQKMVY PGLQEPWLHS MYHGAAFQLT QGDQLSTHTD GIPHLVLSPS TVFFGAFAL
PubMed Link :
TNFbeta+AND+human
Country of Origin :
USA
国内免费服务专线：400 608 7598(据说天才可以在15秒内记住我们的免费电话哦^_^)
服务升级，全新企业QQ为您服务，企业QQ号：4006087598
创赛官网升级为创赛优选商城，请移步www.canspec.cn注册登录，新用户注册送1000元现金券
沪公网安备 31011402005168号
