产品名称：人类卵泡抑制素|Human Follistatin
产品规格：
单 位：瓶
关 键 字：人类卵泡抑制素|Human Follistatin
CANSPEC品质提供的人类卵泡抑制素|Human Follistatin性能**，英文名称人类卵泡抑制素|Human Follistatin，简称为人类卵泡抑制素|Human Follistatin，中文名称为人类卵泡抑制素|Human Follistatin。
产品人类卵泡抑制素|Human Follistatin以其优良的品质满足您不同实验的多种需求。并保证每批人类卵泡抑制素|Human Follistatin的质量和人类卵泡抑制素|Human Follistatin品质优良。English InformationSynonyms :FS, activins-binding proteinDescription :Follistatin is a secreted protein that binds to ligands of the TGF-β family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 31.5 kDa protein containing 288 amino acids. Its primary structure contains three cysteine-rich domains (called FS domains), each followed by a protease-inhibitory kazal domain.Catalog #:120-13Source :E.coilStability :The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted Follistatin is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.Purity :Greater than 95% by SDS-PAGE gel and HPLC analyses.Endotoxin Level :Endotoxin level is less than 0.1 ng per µg (1EU/µg).Biological Activity :Determined by its ability to neutralize Activin A inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.1-0.4 µg/ml in the presence of 7.5 ng/ml Activin A.Selected References :Selected List of References Citing This PeproTech Product AA Sequence : GNCWLRQAKN GRCQVLYKTE LSKEECCSTG RLSTSWTEED VNDNTLFKWM IFNGGAPNCI PCKETCENVD CGPGKKCRMN KKNKPRCVCA PDCSNITWKG PVCGLDGKTY RNECALLKAR CKEQPELEVQ YQGRCKKTCR DVFCPGSSTC VVDQTNNAYC VTCNRICPEP ASSEQYLCGN DGVTYSSACH LRKATCLLGR SIGLAYEGKC IKAKSCEDIQ CTGGKKCLWD FKVGRGRCSL CDELCPDSKS DEPVCASDNA TYASECAMKE AACSSGVLLE VKHSGSCN PubMed Link :Follistatin Country of Origin : USA
Synonyms :
FS, activins-binding protein
Description :
Follistatin is a secreted protein that binds to ligands of the TGF-β family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 31.5 kDa protein containing 288 amino acids. Its primary structure contains three cysteine-rich domains (called FS domains), each followed by a protease-inhibitory kazal domain.
Catalog #:
120-13
Source :
E.coil
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted Follistatin is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :
Determined by its ability to neutralize Activin A inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.1-0.4 µg/ml in the presence of 7.5 ng/ml Activin A.
Selected References :
Selected List of References Citing This PeproTech Product
AA Sequence :
GNCWLRQAKN GRCQVLYKTE LSKEECCSTG RLSTSWTEED VNDNTLFKWM IFNGGAPNCI PCKETCENVD CGPGKKCRMN KKNKPRCVCA PDCSNITWKG PVCGLDGKTY RNECALLKAR CKEQPELEVQ YQGRCKKTCR DVFCPGSSTC VVDQTNNAYC VTCNRICPEP ASSEQYLCGN DGVTYSSACH LRKATCLLGR SIGLAYEGKC IKAKSCEDIQ CTGGKKCLWD FKVGRGRCSL CDELCPDSKS DEPVCASDNA TYASECAMKE AACSSGVLLE VKHSGSCN
PubMed Link :
Follistatin
Country of Origin :
USA
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