产品资料

人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1

产品名称: 人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1
产品型号: C02-120-28-1mg
产品展商: peprotech
产品文档: 无相关文档

简单介绍

人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1系列产品主要适用于试验室或生化科研相关试验,CANSPEC品质提供的人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1性能**,中文名称为人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1。


人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1  的详细介绍

产品名称:人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1

产品规格:

C02-120-28-1mg人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-11mg¥109,200
C02-120-28-20ug人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-120ug¥1,960
C02-120-28-5ug人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-15ug¥680

单        位:瓶

关 键 字:人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1


CANSPEC品质提供的人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1性能**,英文名称人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1,简称为人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1,中文名称为人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1 。

产品人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1以其优良的品质满足您不同实验的多种需求。并保证每批人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1的质量和人分化因子-15/巨噬细胞抑制因子-1|Human GDF-15/MIC-1品质优良。

Synonyms :

MIC-1, Placental TGFβ, Prostate differentiation factor

Description :

GDF-15 belongs to the TGF-β cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in placenta and to a much lesser extent in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest a role for GDF-15 in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers. Human GDF-15/MIC-1 is a disulfide linked homodimeric protein consisting of two 114 amino-acid polypeptide chains.

Catalog #:

120-28

Source :

cell culture

Stability :

The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted GDF-15/MIC-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

Determined by a cell inhibition assay using DU-145 cells. The expected ED50 for this effect is 1.0-2.0 μg/ml.

AA Sequence :

ARNGDHCPLG PGRCCRLHTV RASLEDLGWA DWVLSPREVQ VTMCIGACPS QFRAANMHAQ IKTSLHRLKP DTVPAPCCVP ASYNPMVLIQ KTDTGVSLQT YDDLLAKDCH CI

PubMed Link :

GDF-15+AND+MIC-1

Country of Origin :

USA

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