产品名称：人肌肉生长抑致素|Human Myostatin
产品规格：
单 位：瓶
关 键 字：人肌肉生长抑致素|Human Myostatin
CANSPEC品质提供的人肌肉生长抑致素|Human Myostatin 性能**，英文名称 人肌肉生长抑致素|Human Myostatin，简称为人肌肉生长抑致素|Human Myostatin，中文名称为人肌肉生长抑致素|Human Myostatin。
产品人肌肉生长抑致素|Human Myostatin以其优良的品质满足您不同实验的多种需求。并保证每批人肌肉生长抑致素|Human Myostatin 的质量和人肌肉生长抑致素|Human Myostatin品质优良。English Information Synonyms :GDF-8Description :Myostatin is a TGF-beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin. Recombinant Human myostatin is a 25.0 kDa protein consisting of two identical 109 amino acid polypeptides linked by a single disulfide bond.Catalog #:120-00 Source :E.coli Stability :The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted Myostatin is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.Purity :Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin Level :Endotoxin level is less than 0.1 ng per µg (1EU/µg).Biological Activity :Determined by its ability to inhibit the proliferation of MPC-11 cells. The expected ED50 for this effect is 17.0-25.0 ng/ml.Selected References :Selected List of References Citing This PeproTech ProductAA Sequence :DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS PubMed Link :Myostatin+OR+GDF-8 Country of Origin :USA
Synonyms :
GDF-8
Description :
Myostatin is a TGF-beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin. Recombinant Human myostatin is a 25.0 kDa protein consisting of two identical 109 amino acid polypeptides linked by a single disulfide bond.
Catalog #:
120-00
Source :
E.coli
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted Myostatin is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :
Determined by its ability to inhibit the proliferation of MPC-11 cells. The expected ED50 for this effect is 17.0-25.0 ng/ml.
Selected References :
Selected List of References Citing This PeproTech Product
AA Sequence :
DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS
PubMed Link :
Myostatin+OR+GDF-8
Country of Origin :
USA
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