产品资料

人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian

产品名称: 人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian
产品型号: C02-100-35B-100ug
产品展商: peprotech
产品文档: 无相关文档

简单介绍

人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian系列产品主要适用于试验室或生化科研相关试验，CANSPEC品质提供的人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian性能**，中文名称为人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian。


人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian  的详细介绍

产品名称：人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian

产品规格：

C02-100-35B-100ug人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian100ug￥34,300
C02-100-35B-1mg 人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian1mg￥137,200
C02-100-35B-1ug 人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian1ug￥680
C02-100-35B-500ug 人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian500ug￥82,320
C02-100-35B-5ug 人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian5ug￥1,960

单        位：瓶

关 键 字：人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian


CANSPEC品质提供的人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian 性能**，英文名称人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian，简称为人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian，中文名称为人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian。

产品人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian以其优良的品质满足您不同实验的多种需求。并保证每批人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian的质量和人肿瘤生长因子β2（哺乳动物）|Human TGF-beta2-Mammalian品质优良。


Synonyms :

Transforming Growth Factor-beta2, Glioblastoma-derived T cell suppressor factor, BSC-1, Cetermin, Polyergin

Description :

The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-β2 has been shown to exert suppressive effects on IL-2 dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno-surveillance of tumor development. Recombinant human TGF-β2 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

Catalog #:

100-35B

Source :

A293 cells

Stability :

The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted TGF-β2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

Determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED50 was found to be ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.

Selected References :

Selected List of References Citing This PeproTech Product

AA Sequence :

ALDAAYCFRN VQDNCCLRPL YIDFKRDLGW KWIHEPKGYN ANFCAGACPY LWSSDTQHSR VLSLYNTINP EASASPCCVS QDLEPLTILY YIGKTPKIEQ LSNMIVKSCK CS

PubMed Link :

TGF+AND+beta+AND+2

Country of Origin :

USA

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