产品名称:人血小板源生长因子AA|Human PDGF-AA
产品规格: C02-100-13A-100ug人血小板源生长因子AA|Human PDGF-AA100ug¥13,650C02-100-13A-10ug人血小板源生长因子AA|Human PDGF-AA10ug¥1,960C02-100-13A-1mg人血小板源生长因子AA|Human PDGF-AA1mg¥54,600C02-100-13A-2ug人血小板源生长因子AA|Human PDGF-AA2ug¥680C02-100-13A-500ug人血小板源生长因子AA|Human PDGF-AA500ug¥32,760单 位:瓶
关 键 字:Human PDGF-AA|人血小板源生长因子AA|PDGF-AA
CANSPEC品质提供的人血小板源生长因子AA|Human PDGF-AA性能**,英文名称人血小板源生长因子AA|Human PDGF-AA,简称为人血小板源生长因子AA|Human PDGF-AA,中文名称为人血小板源生长因子AA|Human PDGF-AA。
产品人血小板源生长因子AA|Human PDGF-AA以其优良的品质满足您不同实验的多种需求。并保证每批人血小板源生长因子AA|Human PDGF-AA的质量和人血小板源生长因子AA|Human PDGF-AA品质优良。English InformationSynonyms :Platelet-Derived Growth Factor-AA, Glioma-derived growth factor (GDGF), Osteosarcoma-derived Growth Factor (ODGF)Description :PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-AA is a 28.5 kDa disulfide-linked homodimer of two A chains (250 total amino acids).Catalog #:100-13ASource :E.coliStability :The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted PDGF-AA is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.Purity :Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin Level :Endotoxin level is less than 0.1 ng per µg (1EU/µg).Biological Activity :The ED50 as determined by the dose-dependent stimulation of thymidine uptake by Balb/c 3T3 cells is ≤ 1 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.Selected References :Selected List of References Citing This PeproTech ProductAA Sequence :SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT PubMed Link :PDGF-AACountry of Origin :USA
Synonyms :
Platelet-Derived Growth Factor-AA, Glioma-derived growth factor (GDGF), Osteosarcoma-derived Growth Factor (ODGF)
Description :
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-AA is a 28.5 kDa disulfide-linked homodimer of two A chains (250 total amino acids).
Catalog #:
100-13A
Source :
E.coli
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted PDGF-AA is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by Balb/c 3T3 cells is ≤ 1 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Selected References :
Selected List of References Citing This PeproTech Product
AA Sequence :
SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
PubMed Link :
PDGF-AA
Country of Origin :
USA
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