产品名称:人类胰岛素样生长因子II|Human IGF-II
产品规格:C02-100-12-100ug人类胰岛素样生长因子II|Human IGF-II100ug¥4,900C02-100-12-10ug人类胰岛素样生长因子II|Human IGF-II10ug¥680C02-100-12-1mg人类胰岛素样生长因子II|Human IGF-II1mg¥19,600C02-100-12-500ug人类胰岛素样生长因子II|Human IGF-II500ug¥11,760C02-100-12-50ug人类胰岛素样生长因子II|Human IGF-II50ug¥1,960
单 位:瓶
关 键 字:Human IGF-II|人类胰岛素样生长因子II|Human IGF-II
CANSPEC品质提供的人类胰岛素样生长因子II|Human IGF-II性能**,英文名称人类胰岛素样生长因子II|Human IGF-II,简称为人类胰岛素样生长因子II|Human IGF-II,中文名称为人类胰岛素样生长因子II|Human IGF-II。
产品人类胰岛素样生长因子II|Human IGF-II以其优良的品质满足您不同实验的多种需求。并保证每批人类胰岛素样生长因子II|Human IGF-II的质量和人类胰岛素样生长因子II|Human IGF-II品质优良。English Information Synonyms :Insulin-like Growth Factor-II, Somatamedin ADescription :The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds.Catalog #:100-12Source :E.coliStability :The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted IGF-II is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.Purity :Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin Level :Endotoxin level is less than 0.1 ng per µg (1EU/µg).Biological Activity :The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.Selected References :Selected List of References Citing This PeproTech ProductAA Sequence :AYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE PubMed Link :IGF-IICountry of Origin :USA
Synonyms :
Insulin-like Growth Factor-II, Somatamedin A
Description :
The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds.
Catalog #:
100-12
Source :
E.coli
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted IGF-II is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :
The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Selected References :
Selected List of References Citing This PeproTech Product
AA Sequence :
AYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE
PubMed Link :
IGF-II
Country of Origin :
USA
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