产品名称：人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-3
产品规格：C02-100-08-100ug人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-3100ug￥9,800C02-100-08-1mg人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-31mg￥42,000C02-100-08-25ug人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-325ug￥1,960C02-100-08-500ug人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-3500ug￥25,200C02-100-08-5ug人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-35ug￥680单 位：瓶
关 键 字：Human IGF Binding Protein-3|Human IGF Binding Protein-3|人类胰岛素样生长因子结合蛋白-3
CANSPEC品质提供的人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-3 性能**，英文名称人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-3，简称为人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-3，中文名称为人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-3。
产品人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-3以其优良的品质满足您不同实验的多种需求。并保证每批人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-3的质量和 人类胰岛素样生长因子结合蛋白-3|Human IGF Binding Protein-3品质优良。English InformationSynonyms :Insulin-like Growth Factor-Binding Protein 3, Growth-hormone-dependant binding proteinDescription :IGF-BP3 is a 30 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals and it is also found in α-granules of platelets. In addition to its ability to modulate the activity of IGF-I and IGF-II, IGF-BP3 exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues.Catalog #:100-08Source :E.coliStability :The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted IGF-BP3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.Purity :Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin Level :Endotoxin level is less than 0.1 ng per µg (1EU/µg).Biological Activity :The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7. The expected ED50 for this effect is ≤ 0.2 µg/ml in presence of 15 ng/ml of human IGF-II.AA Sequence :GASSGGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG EVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK PubMed Link :IGF+AND+Binding+AND+Protein-3Country of Origin :USA
Synonyms :
Insulin-like Growth Factor-Binding Protein 3, Growth-hormone-dependant binding protein
Description :
IGF-BP3 is a 30 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals and it is also found in α-granules of platelets. In addition to its ability to modulate the activity of IGF-I and IGF-II, IGF-BP3 exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues.
Catalog #:
100-08
Source :
E.coli
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted IGF-BP3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :
The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7. The expected ED50 for this effect is ≤ 0.2 µg/ml in presence of 15 ng/ml of human IGF-II.
AA Sequence :
GASSGGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG EVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK
PubMed Link :
IGF+AND+Binding+AND+Protein-3
Country of Origin :
USA
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