产品名称：人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5
产品规格：C02-100-05-100ug人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5100ug￥9,800C02-100-05-1mg人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-51mg￥42,000C02-100-05-25ug人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-525ug￥1,960C02-100-05-500ug人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5500ug￥25,200C02-100-05-5ug人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-55ug￥680
单 位：瓶
关 键 字：Human IGF Binding Protein-5|Human IGF Binding Protein-5|人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5
CANSPEC品质提供的人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5性能**，英文名称人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5，简称为人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5，中文名称为人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5。
产品人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5以其优良的品质满足您不同实验的多种需求。并保证每批人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5的质量和人类胰岛素样生长因子结合蛋白-5|Human IGF Binding Protein-5品质优良。English InformationSynonyms : Insulin-like Growth Factor-Binding Protein5Description :IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP-5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development. Recombinant human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.Catalog #:100-05Source :E.coliStability :The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted IGF-BP5 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.Purity :Greater than 98% by SDS-PAGE gel and HPLC analysesEndotoxin Level :Endotoxin level is less than 0.1 ng per μg (1EU/μg).Biological Activity :The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is ≤ 0.3 μg/ml in the presence of 15 ng/ml of human IGF-II.AA Sequence :MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS PubMed Link :IGF Binding Protein 5Country of Origin :USA
Synonyms :
Insulin-like Growth Factor-Binding Protein5
Description :
IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP-5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development. Recombinant human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.
Catalog #:
100-05
Source :
E.coli
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted IGF-BP5 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses
Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Biological Activity :
The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is ≤ 0.3 μg/ml in the presence of 15 ng/ml of human IGF-II.
AA Sequence :
MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
PubMed Link :
IGF Binding Protein 5
Country of Origin :
USA
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