IGFBP4 蛋白产品信息 产品名称:重组人 IGFBP4 蛋白|Insulin-Like Growth Factor Binding Protein 4 |技术资料|价格 IGFBP4 别名: BP-4, HT29-IGFBP, IBP4, IGFBP-4, IGFBP4 表达方式: A DNA sequence encoding the human IGFBP4 (NP_001543.2) precursor (Met 1- Glu 258) with a C-terminal polyhistidine tag was expressed. 种属: Human 表达宿主: Human Cells IGFBP4 蛋白质控指标 纯度: > 95%, as determined by SDS-PAGE SDS-PAGE 内**: < 1.0 EU per 1μg of the protein as determined by the LAL method. 稳定性: Samples are stable for up to twelve months from date of receipt at -70℃ 预测N端: Asp 22 分子量: The secreted recombinant human IGFBP4 comprises 248 amino acids with a predicted molecular mass of 27.4 kDa. As a result of glycosylation, it migrates as an approximately 32 kDa band in SDS-PAGE under reducing conditions. 缓冲液: Lyophilized from sterile PBS , pH 7.4 Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. IGFBP4蛋白使用指南 储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. IGFBP4 蛋白背景综述 Insulin-like growth factor-binding proteins (IGFBPs) control bioavailability, activity, and distribution of insulin-like growth factor (IGF) through high-affinity IGFBP/IGF complexes. Six high-affinity IGF-binding proteins (IGFBP-1 to -6) have been identified, and IGFBP4, the smallest IGFBP expressed by a wide range of cell types, exists in both non-glycosylated and N-glycosylated forms in all biological fluids. Structurally consisting of an IGFBP domain and a thyroglobulin type-I domain, IGFBP4 binds IGF-I and IGF-II with similar affinities as a transport protein and modulates their biological effects. Increasing evidences indicate that IGFBP4 inhibits IGF-induced cellular growth both in vitro and in vivo. As an important member of the IGF system, IGFBP4 is involved in a wide range of biological processes including reproductive physiology, bone formation, renal pathophysiology and carcinomas. 参考文献 Durai, R. et al., 2006, Int. J. Oncol. 28: 1317-1325. Sitar, T. et al., 2006, Proc. Natl. Acad. Sci. U.S.A. 103: 13028-13033. Zhou, R. et al., 2003, J. Endocrinol. 178: 177-193. Zhou, J. et al., 2003, Biol. Reprod. 69: 22-29. 包装:5ug 20ug
1、产品质量问题,在产品售出7日内提出异议并且产品未有损坏,试剂类产品,需要提供详细的检测数据,创赛负责免费退换货服务; 2、本产品属于消耗品,不提供质保服务; 3、所有产品售后问题,请直接联系我司,我们将会尽快为您响应处理 查询关键词:重组人 IGFBP4 蛋白,Insulin-Like Growth Factor Binding Protein 4 ,技术资料,价格,原料药,大包装定制,现货促销,医药中间体,科学仪器,实验室耗材,生化试剂,创赛中国,细胞因子 CANSPEC品质提供的重组人 IGFBP4 蛋白|Insulin-Like Growth Factor Binding Protein 4 |技术资料|价格性能**,其优良的品质满足您不同实验的多种需求。 本产品由上海创赛品质提供,欢迎咨询国内免费服务专线:400-608-7598,更多产品信息请登录www.canspecsci.com或www.4006087598.com
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