重组人 aFGF / FGF1 蛋白|Acidic Fibroblast Growth Factor ( aFGF / FGF1 ) Protein|价格

aFGF / FGF1蛋白产品信息
产品名称：重组人 aFGF / FGF1 蛋白|Acidic Fibroblast Growth Factor ( aFGF / FGF1 ) Protein|价格
aFGF 别名: aFGF, FGF1, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1
Protein Construction: A DNA sequence encoding the mature form of human FGF acidic ( AAA79245.1 )( Phe 16 - Asp 155 ) was expressed, with an additional Met at the N-terminus.
种属: Human
表达宿主: E. coli

aFGF / FGF1 Protein QC Testing
纯度: > 95% as determined by SDS-PAGE SDS-PAGE
Bio-activity: Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts.
The ED50 for this effect is typically  50 - 200 pg/ml
内**: Please contact us for more information..
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Met 1
分子量: The recombinant human FGF acidic consists of 141 amino acids and has a calculated molecular mass of 16 kDa as estimated by SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS , pH 7.4
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
aFGF / FGF1 Protein Usage Guide
储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
aFGF / FGF1 Protein Related Products & Topics

aFGF / FGF1 Protein Description
aFGF (Acidic fibroblast growth factor), also known as FGF1 (Fibroblast growth factor 1), FGF-acidic and HBGF-1 (Heparin-binding growth factor 1), is a member of the fibroblast growth factor (FGF) family. It is a powerful mitogen exhibiting strong action on numerous different cell types. FGF1 protein plays a role in various stages of development and morphogenesis, as well as in angiogenesis and wound healing processes. aFGF protein binds to cell surface receptors with high affinity with the prerequisite association of aFGF with heparan sulfate. The aFGF gene is a repressed target of p53. It inhibits both p53-dependent apoptosis and cell growth arrest via an intracrine pathway. Accordingly, aFGF and p53 pathways may interact in the cell to determine cell fate.
参考文献
Rothlein, R. et al.,1986, Journal of Immunology. 137 (4): 1270–1274.
Yang, L. et al., 2005, Blood 106 (2): 584–592.
Gorczynski, R.M., 2005, Curr. Opin. Invest. Drugs. 6:483-487.
Frijns, C.J. et al., 2002, Stroke 33 (8): 2115–2122.
Bella, J. et al., 1998, Proc. Natl. Acad. Sci. U.S.A. 95 (8): 4140–4145.

包装：5ug  50ug  500ug 

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