FGF9 / GAF Protein Product Information 产品名称:重组人 FGF9 蛋白|Fibroblast Growth Factor 9 ( FGF9 / GAF ) Protein|厂家报价|参数 FGF9 Synonym: FGF9, GAF, HBFG-9, MGC119914, MGC119915 Protein Construction: A DNA sequence encoding the mature form of human fibroblast growth factor 9 ( NP_002001.1 ) ( Leu 4 - Ser 208 ) was expressed with the fused Fc region of human IgG1 at the N-terminus Source: Human Expression Host: Human Cells FGF9 / GAF Protein QC Testing Purity: (81.9 + 13.9) %, as determined by SDS-PAGE SDS-PAGE Bio-activity:Measured in a cell proliferation assay using Balb/c3T3 mouse embryonic fibroblasts. ( Rubin, J.S. et al. 1991. Proc. Natl. Acad. Sci. USA 88: 415. ) The ED50 for this effect is typically 1 - 3 ng/mL Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method. Stability: Samples are stable for up to twelve months from date of receipt at -70℃ Predicted N terminal: Glu 20 Molecular Mass: The recombinant human Fc/FGF9 is a disulfide-linked homodimeric protein. The reduced monomer consists of 463 amino acids and has a predicted molecular mass of 54 and 37 kDa as estimated in SDS-PAGE under reducing conditions duo to glycosylation. Formulation: Lyophilized from sterile PBS , pH 7.4 Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. FGF9 / GAF Protein Usage Guide Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage and usage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. FGF9 / GAF Protein Description Fibroblast growth factor (FGF) family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, tumor growth and invasion. FGF9, also designated as glia-activating factor (GAF), was purified originally as a heparin-binding, secreted glycoprotein from cultured human glioma cell line and exhibits a growth-stimulating effect on glial cells. FGF9 is also a mitogen for oligodendrocyte type 2 astrocyte progenitor cells, smooth muscle cells, pheochromocytoma PC12 cells, and BALB/3T3 fibroblasts. However, unlike FGF acidic and basic, FGF9 has no effect on human umbilical vein endothelial cells, and it has been demonstrated that FGF9 binds preferentially to the IIIc form of FGFR3. Although no typical signal sequence was found in FGF9, it is secreted efficiently after synthesis not in a conventional manner. In nervous system, FGF9 is produced mainly by neurons and may plays an important role in CNS development References
Naruo, K. et al., 1993, J. Biol. Chem. 268: 2857-2864. Miyamoto, M. et al., 1993, Mol. Cell. Biol. 13: 4251-4259. DiNapoli, L. et al., 2006, Development. 133: 1519-1527. 包装:5ug 20ug
1、产品质量问题,在产品售出7日内提出异议并且产品未有损坏,试剂类产品,需要提供详细的检测数据,创赛负责免费退换货服务; 2、本产品属于消耗品,不提供质保服务; 3、所有产品售后问题,请直接联系我司,我们将会尽快为您响应处理 查询关键词:重组人 FGF9 蛋白,Fibroblast Growth Factor 9 ( FGF9 / GAF ) Protein,厂家报价,参数,原料药,大包装定制,现货促销,医药中间体,科学仪器,实验室耗材,生化试剂,创赛中国,细胞因子 CANSPEC品质提供的重组人 FGF9 蛋白|Fibroblast Growth Factor 9 ( FGF9 / GAF ) Protein|厂家报价|参数性能**,其优良的品质满足您不同实验的多种需求。 本产品由上海创赛品质提供,欢迎咨询国内免费服务专线:400-608-7598,更多产品信息请登录www.canspecsci.com或www.4006087598.com
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