重组人 FGF10 蛋白|Fibroblast growth factor 10 Protein|产品详情|现货

FGF10蛋白产品信息
产品名称：重组人 FGF10 蛋白|Fibroblast growth factor 10 Protein|产品详情|现货
FGF10 别名: FGF10
表达方式: A DNA sequence encoding the mature form of human FGF10 (NP_004456.1) (Gln 38- Ser 208) was expressed.
种属: Human
表达宿主: E.coli

FGF10蛋白质控指标
纯度: ﹥98 % as determined by SDS-PAGE. SDS-PAGE
内**: < 1.0 EU per 1μg of the protein as determined by the LAL method.
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Met
分子量: The recombinant human FGF10 consists of 172 amino acids and has a predicted molecular mass of 19.6 KDa as estimated in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile 20mM Tris, pH7.5
FGF10蛋白使用指南
储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted and be used as soon as possible.; Avoid repeated freeze-thaw cycles
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
FGF10 Protein Related Products &Topics

FGF10蛋白背景综述
The fibroblast growth factors (FGFs) are a growing family of heparin-binding growth factors that that regulate a variety of physiological processes in both developing and ***** organism. The secreted human FGF10 exists most abundantly in the embyro and ***** lung, and is most closely related to FGF7. It signaling through FGF receptor 2 (FGFR2) controls survival, proliferation, and differentiation of distal-alveolar epithelial progenitor cells during lung development. FGF10 overexpression during both the inflammatory and fibrotic phases results in a greatly reduced extent of lung fibrosis, suggesting that FGF10 may be useful as a novel approach to the treatment of pulmonary fibrosis. Additionally, FGF10 is also proposed as a growth factor active involved in the process of wound healing and limb bud formation. Human FGF10 shares approximately 92% and 95% amino acid sequence identity with mouse and rat FGF10, respectively.
参考文献
Krejci P. et al., 2009, Hum Mutat. 30(9):1245-1255.
Abler L.L. et al., 2009, Dev Dyn. 238(8):1999-2013.
Gupte V.V. et al., 2009, Am J Respir Crit Care Med. 180(5):424-436.
Carraro G. et al., 2009, Dev Biol. 333(2):238-250.

包装：5ug  50ug

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