重组人 EphrinB1 / EFNB1 蛋白|Ephrin-B1 / EFNB1 / ELK-L Protein|产品详情|现货

EFNB1蛋白产品信息
产品名称：重组人 EphrinB1 / EFNB1 蛋白|Ephrin-B1 / EFNB1 / ELK-L Protein|产品详情|现货
别名: EFNB1,RP3-496G1.1, CFND, CFNS, EFL3, EPLG2, Elk-L, LERK2,
Protein Construction: A DNA sequence encoding the human EFNB1 (NP_004420.1) extracellular domain (Met 1- Gly 232) was fused with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

EFNB1蛋白质控指标
纯度: >95% as determined by SDS-PAGE. SDS-PAGE:
内**: < 1.0 EU per μg of the protein as determined by the LAL method.
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Leu 28
分子量: The recombinant human EFNB1 consists of 221 amino acids and predicts a molecular mass of 24.5 KDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh EFNB1 is approximately 38 KDa due to glycosylation.
缓冲液: 
Lyophilized from 0.2μm filtered solution of PBS, pH7.4
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
 
EFNB1蛋白使用指南
储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted and be used as soon as possible. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
EFNB1 Protein Description
The ephrins (Eph) and Eph receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. All ephrins share a conserved extracellular sequence, which most likely corresponds to the receptor-binding domain. In molecular biology, ephrins and Eph receptors are components of cell signaling pathways involved in animal development, and implicated in some cancers. Ephrin-B1, also known as LERK-2, ELK-L, EFL-3, Cek5-L, and STRA-1, is a member of the ephrin ligand family which binds members of the Eph receptor family. Ephrin-B1 has been shown to bind EphA3, EphB1, EphB2, EphB3, and EphB4. The extracellular domains of human and mouse ephrin-B1 share 94% amino acid identity.
EFNB1 Protein Related Products & Topics
参考文献
Cerretti, DP. et al., 1995, Mol. Immunol. 32 (16): 1197-205.
Gale, NW. et al.,1996, Neuron.17 (1): 9-19.
Flanagan, J. et al., 1998, Annual Review of Neuroscience. 21: 309-45.
Holder, N. et al., 1999,  Development. 126 (10): 2033-44.
Wilkinson, DG. et al., 2001, Nat. Rev. Neurosci. 2 (3): 155-64.
Murai, KK. et al., 2003, Journal of Cell Science. 116 (Pt 14): 2823-32.

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