重组人 CCL22 / MDC 蛋白|Chemokine (C-C motif) ligand 22 Protein|生产厂家|现货

CCL22 / MDC蛋白产品信息
产品名称：重组人 CCL22 / MDC 蛋白|Chemokine (C-C motif) ligand 22 Protein|生产厂家|现货
别名: A-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1
表达方式: A DNA sequence encoding the secreeted form of human CCL22 (O00626) (Gly 25-Gln 93 ) was expressed, with a polyhistidine tag at the N-terminus.
种属: Human
表达宿主: E.coli

CCL22 / MDC蛋白质控指标
纯度: > 90 % as determined by SDS-PAGE SDS-PAGE
内**: Please contact us for more information.
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Met
分子量: The recombinant human CCL22 consisting of 84 amino acids and has a calculated molecular mass of 9.7 KDa. It migrates as an 10 kDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile 30% Acetonitrile，0.1% TFA
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
CCL22 / MDC蛋白使用指南

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CCL22 / MDC蛋白背景综述
Macrophage-derived chemokine (MDC), also known as CCL22, is a CC chemokine which shows chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. CCL22 gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL22 displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. CCL22 binds to chemokine receptor CCR4 and may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.
参考文献
Godiska R. et al., 1997, J Exp Med. 185 (9): 1595-604.
Nomiyama H. et al., 1998, Cytogenet Cell Genet. 81 (1): 10-1.
Vulcano M. et al., 2001, Eur J Immunol. 31 (3): 812-22.
Nomiyama H. et al., 1998, Cytogenet Cell Genet. 81 (1): 10-1.

包装：20ug

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