重组人 CXCL5 蛋白|Chemokine (C-X-C motif) ligand 5 Protein|技术资料|参数

CXCL5蛋白产品信息
产品名称：重组人 CXCL5 蛋白|Chemokine (C-X-C motif) ligand 5 Protein|技术资料|参数
别名: CXCL5, ENA78, SCYB5
表达方式: A DNA sequence encoding the human CXCL5 (P42830) (Arg45-Asn114) was expressed, with a N-terminal Met.
种属: Human
表达宿主: E.coli

CXCL5 Protein QC Testing
纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: Please contact us for more information.
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Met
分子量: The recombinant human CXCL5 consists of  71 amino acids and predicts a molecular mass of 7.8 KDa. It migrates as an approximately 8 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile 80% acetonitrile 0.1%TFA 20%H2O.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CXCL5 Protein Usage Guide
储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
CXCL5蛋白背景综述
CXCL5 is a small cytokine which belongs to the CXC chemokine family. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. It is expressed in eosinophils, and can be inhibited with the type II interferon. CXCL5 is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. It plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which can be utilized to understand more about pain in other inflammatory conditions like arthritis and cystitis. It also stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. CXCL5 has been implicated in connective tissue remodelling.
参考文献
Dawes JM. et al., 2011, Sci Transl Med. 3 (90): 90ra60.
O'Donovan N. et al., 1999, Cell Genet. 84 (1-2): 39-42.
Persson T. et al., 2003, Clin Exp Allergy. 33 (4): 531-7.

包装：20ug

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