重组人 CXCL14 / BRAK 蛋白|Chemokine (C-X-C motif) ligand 14 Protein|生产厂家|价格

CXCL14 / BRAK蛋白产品信息
产品名称：重组人 CXCL14 / BRAK 蛋白|Chemokine (C-X-C motif) ligand 14 Protein|生产厂家|价格
别名: CXCL14, MIP2G, NJAC, SCYB14
表达方式: 
A DNA sequence encoding human CXCL14 (O95715) (Ser35-Glu111) was expressed with a N-terminal Met.
种属: Human
表达宿主: E.coli

CXCL14 / BRAK Protein QC Testing
纯度: > 90 % as determined by SDS-PAGE SDS-PAGE
内**: Please contact us for more information.
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Met
分子量: The recombinant human CXCL14 consists of  77 amino acids and predicts a molecular mass of 9.4 KDa. It migrates as an approximately 15 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile 100mM NaH2PO4, 1M NaCl, pH 6.5.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CXCL14 / BRAK Protein Usage Guide
储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CXCL14 / BRAK蛋白背景综述
CXCL14, also known as BRAK, is a small cytokine belonging to the CXC chemokine family. Members of this family are secreted proteins involved in immunoregulatory and inflammatory processes. CXCL14 is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. It is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. CXCL14 functions as a potent chemoattractant for neutrophils. It also has weaker attraction for dendritic cells. However, CXCL14 is not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. CXCL14 does not inhibit proliferation of myeloid progenitors in colony formation assays.
参考文献
Tarnes T. et al., 2006, Exp Hematol. 34 (8): 1101-5.
Shurin G V. et al., 2005, J Immun. 174: 5490-8.
Kurth I. et al., 2001, J Exp Med. 194: 855-61.
Frederick M J. et al., 2000, Am J Path. 156: 1937-50.

包装：20ug

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