重组人 ANG2 / Angiopoietin-2 蛋白|Angiopoietin-2 / ANG2 Protein|厂家现货|参数

ANGPTL1 / Angiopoietin-like 1蛋白产品信息
产品名称：重组人 ANG2 / Angiopoietin-2 蛋白|Angiopoietin-2 / ANG2 Protein|厂家现货|参数
别名: ANGPTL1
表达方式: A DNA sequence encoding the canine ANGPTL1 (E2RQY3) (Glu197-Asp491) was expressed with the Fc region of human IgG1 at the N-terminus.
种属: Canine
表达宿主: Human Cell

ANGPTL1 / Angiopoietin-like 1 Protein QC Testing
纯度: (64.2+28.7) % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Glu
分子量: The recombinant canine ANGPTL1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 555 amino acids and has a predicted molecular mass of 62.4 kDa. The apparent molecular mass of the protein is approximately 64 and 38 kDa in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
ANGPTL1 / Angiopoietin-like 1 Protein Usage Guide

储存方法:  Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Reconstitution:  A hardcopyAngiopoietin-2 / ANG2蛋白产品信息
别名: AGPT2,   ANG2,   ANGPT2
表达方式: 
A DNA sequence encoding the human Angiopoietin 2 ( NP_001138.1 ) ( Met 1 -  Phe 496 ) was expressed, fused with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

Angiopoietin-2 / ANG2蛋白质控指标
纯度: > 92 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Tyr 19
分子量: The recombinant human Ang2 consists of 489 amino acids and predicts a molecular mass of 56.3 kDa. As a result of glycosylation, the rhAng2 migrates as approximately 60-70 kDa band in SDS-PAGE under reducing conditions
缓冲液: 
Lyophilized from sterile PBS , pH 7.4
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

Angiopoietin-2 / ANG2蛋白使用指南
储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Angiopoietin-2 / ANG2蛋白背景综述
Angiopoietin 2 (Ang2), closely related to Ang1, is a secreted ligand which binds to the endothelial-specific receptor tyrosine kinase Tie2 with similar affinity. Ang2 is a soluble 70kd growth factor consisting of an amino-terminal coiled-coil domain and a carboxy-terminal fibrinogen-like domain. Tie2 and angiopoietins have been shown to play critical roles in vessel remodeling during angiogenesis, vascular homeostatic responses, and the ***** vasculature integrity. Ang2 was initially characterized as an antagonist of Ang1 and Tie2, which competitively inhibit Ang1-induced endothelial cell responses mediated by Tie2, and reduces vascular integrity. But the role of Ang2 is controversial since the opposite outcomes has been reported in other studies. Over-expression of Ang2 disrupts the vascular remodeling, induce endothelial cell apoptosis, and may play an important regulating role in tumor angiogenesis.
参考文献
Maisonpierre, P.C. et al., 1997, Science 277: 55-60
Bezuidenhout, L. et al., 2007, J. Leukoc. Biol. 81: 1496-1503.
Tanaka, S. et al., 1999, J. Clin. Invest. 103: 341-345.
Yu, Q. et al., 2001, Am. J. Pathol. 158: 563-570.
Teichert-Kuliszewska, K. et al., 2001, Circ. Res. 49, 659-670.
Schliemann, C. et al., 2007, Leukemia. 21: 1901-1906. of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

包装：20ug

1、产品质量问题，在产品售出7日内提出异议并且产品未有损坏，试剂类产品，需要提供详细的检测数据，创赛负责免费退换货服务；
2、本产品属于消耗品，不提供质保服务；
3、所有产品售后问题，请直接联系我司，我们将会尽快为您响应处理
查询关键词：重组人 ANG2 / Angiopoietin-2 蛋白,Angiopoietin-2 / ANG2 Protein,厂家现货,参数，原料药，大包装定制，现货促销，医药中间体，科学仪器，实验室耗材，生化试剂，创赛中国,细胞因子
CANSPEC品质提供的重组人 ANG2 / Angiopoietin-2 蛋白|Angiopoietin-2 / ANG2 Protein|厂家现货|参数性能**，其优良的品质满足您不同实验的多种需求。
本产品由上海创赛品质提供，欢迎咨询国内免费服务专线：400-608-7598，更多产品信息请登录www.canspecsci.com或www.4006087598.com