重组大鼠 LTBR 蛋白|LTBR Protein|技术资料|现货

LTBR蛋白产品信息
产品名称：重组大鼠 LTBR 蛋白|LTBR Protein|技术资料|现货
别名: LTBR
表达方式: 
A DNA sequence encoding the rat LTBR (NP_001008316.1 ) extracellular domain (Met 1-Ala 218) was expressed, fused with a polyhistidine tag at the C-terminus.
种属: Rat
表达宿主: Human Cells

LTBR蛋白质控指标
纯度: > 96 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Ser 28
分子量: The recombinant rat LTBR comprises 202 amino acids and predicts a molecular mass of 23 kDa. The apparent molecular mass of the ratLTBR is approximately 35 kDa in SDS-PAGE under reducing conditions due to glycosylation.
缓冲液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

LTBR蛋白使用指南
储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

LTBR蛋白背景综述
LTBR (lymphotoxin beta receptor (TNFR superfamily, member 3)) contains 4 TNFR-Cys repeats and belongs to the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. It is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs. LTBR has been shown to interact with diablo homolog and TRAF3. It can lead to the release of the cytokine interleukin 8. Overexpression of LTBR in HEK293 cells increases IL-8 promoter activity and leads to IL-8 release. LTBR is also essential for development and organization of the secondary lymphoid organs and chemokine release. It specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and transformed cells.
参考文献
Summers deLuca L. et al., 2011, Proc Natl Acad Sci. 108 (5): 2046-51.
Bista P. et al., 2010, J Biol Chem. 285 (17): 12971-8.
Xu Y. et al., 2011, Biochem Biophys Res Commun. 404 (4): 1060-4.
包装：50ug

1、产品质量问题，在产品售出7日内提出异议并且产品未有损坏，试剂类产品，需要提供详细的检测数据，创赛负责免费退换货服务；
2、本产品属于消耗品，不提供质保服务；
3、所有产品售后问题，请直接联系我司，我们将会尽快为您响应处理
查询关键词：重组大鼠 LTBR 蛋白,LTBR Protein,技术资料,现货，原料药，大包装定制，现货促销，医药中间体，科学仪器，实验室耗材，生化试剂，创赛中国,细胞因子
CANSPEC品质提供的重组大鼠 LTBR 蛋白|LTBR Protein|技术资料|现货性能**，其优良的品质满足您不同实验的多种需求。
本产品由上海创赛品质提供，欢迎咨询国内免费服务专线：400-608-7598，更多产品信息请登录www.canspecsci.com或www.4006087598.com