CD63 / Tspan-30 / Tetraspanin-30蛋白产品信息 产品名称:重组野猪 CD63 / Tspan-30 / Tetraspanin-30 蛋白|Cd63 molecule Protein| 厂家现货|参数 别名: CD63 表达方式: A DNA sequence encoding the Sus scrofa (Pig) CD63 (XP_003355519.1) (Arg 108-Phe 204) was fused with the human IgG1 Fc region at the N-terminus. 种属: Sus scrofa (Pig) 表达宿主: Human Cells CD63 / Tspan-30 / Tetraspanin-30蛋白质控指标 纯度: > 95 % as determined by SDS-PAGE SDS-PAGE 内**: < 1.0 EU per μg of the protein as determined by the LAL method 稳定性: Samples are stable for up to twelve months from date of receipt at -70℃ 预测N端: Gln 22 分子量: The secreted recombinant Sus scrofa (Pig) CD63/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 338 amino acids and has a predicted molecular mass of 38.2 kDa. It migrates as an approximately 48 kDa band in SDS-PAGE under reducing conditions due to glycosylation. 缓冲液: Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. CD63 / Tspan-30 / Tetraspanin-30蛋白使用指南 储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. CD63 / Tspan-30 / Tetraspanin-30蛋白背景综述 CD63 antigen, also known as Granulophysin, Lysosomal-associated membrane protein 3, Melanoma-associated antigen ME491, Ocular melanoma-associated antigen, Tetraspanin-30, CD63 and Tspan-30, is a multi-pass membrane protein which belongs to the tetraspanin (TM4SF) family. Tetraspanins comprise a large superfamily of cell surface-associated membrane proteins characterized by four transmembrane domains. Tetraspanins participate in a variety of cellular processes, like cell activation, adhesion, differentiation and tumour invasion. At the cell surface, tetraspanins form networks with a wide diversity of proteins called tetraspanin-enriched microdomains (TEMs). CD63 / Tspan-30 was the first characterized tetraspanin. In addition to its presence in TEMs, CD63 / Tspan-30 is abundantly present in late endosomes and lysosomes. CD63 / Tspan-30 is expressed in melanoma and appears to be involved in regulation of motility and adhesion of melanoma cells. CD63 / Tspan-30 is associated with early stages of melanoma tumor progression. It may play a role in growth regulation. Lack of expression of CD63 in platelets has been observed in a patient with Hermansky-Pudlak syndrome (HPS). which is a genetically heterogeneous, rare, autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. 参考文献 Smith M. et al., 1997, Melanoma Res. 7 (2): S163-70. Chen Z. et al., 2004, Int J Mol Med. 14 (4): 517-27. Iida J. et al., 2005, J Transl Med. 3: 42. K?llquist L. et al., 2008, Blood. 112 (8): 3444-54. Pols MS. et al., 2009, Exp Cell Res. 315 (9): 1584-92. 包装:20ug
1、产品质量问题,在产品售出7日内提出异议并且产品未有损坏,试剂类产品,需要提供详细的检测数据,创赛负责免费退换货服务; 2、本产品属于消耗品,不提供质保服务; 3、所有产品售后问题,请直接联系我司,我们将会尽快为您响应处理 查询关键词:重组野猪 CD63 / Tspan-30 / Tetraspanin-30 蛋白,Cd63 molecule Protein,厂家现货,参数,原料药,大包装定制,现货促销,医药中间体,科学仪器,实验室耗材,生化试剂,创赛中国,细胞因子 CANSPEC品质提供的重组野猪 CD63 / Tspan-30 / Tetraspanin-30 蛋白|Cd63 molecule Protein| 厂家现货|参数性能**,其优良的品质满足您不同实验的多种需求。 本产品由上海创赛品质提供,欢迎咨询国内免费服务专线:400-608-7598,更多产品信息请登录www.canspecsci.com或www.4006087598.com
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