Rat IFN-alpha / IFNA1 / IFN Protein|厂家现货|价格

IFN-alpha / IFNA1 / IFN蛋白产品信息

别名: IFNA1
表达方式: 
A DNA sequence encoding the rat IFNA1 (P05011) (Met1-Ser192) was expressed, fused with a polyhistidine tag at the C-terminus.
种属: Rat
表达宿主: Human Cells

IFN-alpha / IFNA1 / IFN Protein QC Testing

纯度: > 99 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Cys 24
分子量: The recombinant rat IFNA1 comprises 180 amino acids and predicts a molecular mass of 20.9 kDa. The apparent molecular mass of the rat IFNA1 is approximately 20-25 kDa in SDS-PAGE under reducing conditions due to glycosylation.
缓冲液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

IFN-alpha / IFNA1 / IFN Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

IFN-alpha / IFNA1 / IFN蛋白背景综述

IFN (interferon-alpha 1,human IgG1-Fc chimera), also known as IFN-alpha, IFNA13 and IFNA1, belongs to the alpha/beta interferon family. IFNs belong to the large class of glycoproteins known as cytokines. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon (IFN-gamma) is produced by mitogen- or antigen-stimulated antigen-stimulated T lymphocytes. IFNs are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. Produced by macrophages, IFN have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they also increase the ability of uninfected host cells to resist new infection by virus.

参考文献

Olopade OI. et al., 1992, Genomics. 14 (2): 437-43.
Conti L. et al., 2005, Immunobiology. 209 (1-2): 99-115.
Bekisz J. et al., 2005, Growth Factors. 22 (4): 243-51.

规格：50ug

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