Mouse ApoA1 Protein|技术资料|现货|价格

ApoA1蛋白产品信息

别名: ApoA1
表达方式: 
A DNA sequence encoding the mouse ApoA1 (Q00623) (Met1- Gln264) was expressed with a C-terminal polyhistidine tag.
种属: Mouse
表达宿主: Human Cells

ApoA1 Protein QC Testing

纯度: >94% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Trp 19
分子量: 
The recombinant mouse ApoA1 comprises 257 amino acids and has a predicted molecular mass of 30.2 kDa. The apparent molecular mass of the protein is approximately 27-31 kDa in SDS-PAGE under reducing conditions due to glycosylation.
缓冲液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

ApoA1 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

ApoA1蛋白背景综述

Apolipoprotein A1 (APOA1) is the main component of high density lipoprotein (HDL) in plasma and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase(LCAT) which is responsible for the formation of most plasma cholesteryl esters. and thus play a major role in cholesterol efflux from peripheral cells. APOA1 is also characterized as a prostacyclin stabilizing factor, and thus may have an anticlotting effect. Defects in encoding gene may result in HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. As a major component of the HDL complex, APOA1 helps to clear cholesterol from arteries. Men carrying a mutation may develop premature coronary artery disease.

参考文献

Toptas B. et al., 2011, In Vivo. 25 (3): 425-30.
Haase CL. et al., 2011, J Intern Med. 270 (2): 136-46.
Wu Z. et al., 2011, J Biol Chem. 286 (14): 12495-508.

规格：100ug

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