Rat CLEC1 / CLEC1A Protein|产品详情|技术资料

CLEC1 / CLEC1A蛋白产品信息

别名: CLEC1A
表达方式: A DNA sequence encoding the rat CLEC1A(D3ZGU3)(Gln73-Gln269) was expressed, fused with Fc region of human IgG1 at the N-terminus.
种属: Rat
表达宿主: Human Cells

CLEC1 / CLEC1A Protein QC Testing

纯度: > 69 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Glu
分子量: 
The recombinant rat CLEC1A comprises 457 amino acids and predicts a molecular mass of 51.6 kDa. The apparent molecular mass of  the recombinant protein is approximately 65 kDa in SDS-PAGE under reducing conditions due to glycosylation.
缓冲液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CLEC1 / CLEC1A Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CLEC1 / CLEC1A蛋白背景综述

CLEC1A, also known as CLEC-1, belongs to the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. It contains 1 C-type lectin domain and is expressed preferentially in dendritic cells. It is found that CLEC1A not only expressed in dendritic cells, but also in endothelial cells and in the latter aspect resembles the LOX-1 gene. CTL/CTLD superfamily is composed by proteins that share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC1A may play a role in regulating dendritic cell function. CLEC1A gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. Alternative splice variants have been described but their biological nature has not been determined.

参考文献

Ebner S. et al., 2003, Proteins. 53 (1): 44-55.
Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.
Drickamer K. 1999, Curr Opin Struct Biol. 9 (5): 585-90.

规格：50ug

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