CCDC47 Protein|CCDC47蛋白质|厂家现货|参数

CCDC47蛋白产品信息

别名: CCDC47
表达方式: 
A DNA sequence encoding the human CCDC47 (Q96A33-1) (Met1-Ser135) was expressed with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

CCDC47 Protein QC Testing

纯度: > 95% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Lys 21
分子量: 
The recombinant human CCDC47 consists of  126 amino acids and predicts a molecular mass of 14.7 KDa. It migrates as an approximately  22 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CCDC47 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CCDC47蛋白背景综述

CCDC47 gene contains 16 distinct gt-ag introns. Transcription produces 9 different mRNAs, 6 alternatively spliced variants and 3 unspliced forms. There are 3 probable alternative promotors, 3 non overlapping alternative last exons and 8 validated alternative polyadenylation sites. CCDC47 gene is expressed at high level. The gene The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of a cassette exon, overlapping exons with different boundaries. Functionally, CCDC47 gene has been proposed to participate in processes such as calcium ion homeostasis, embryo development, ER overload response and post-embryonic development. CCDC47 are expected to have molecular function (calcium ion binding) and to localize in various compartments (membrane, endoplasmic reticulum, integral to membrane, microsome.

参考文献

Li S. et al., 2011, Immunity. 35 (3): 426-40.
Danielsen JM. et al., 2011, Mol Cell Proteomics. 10 (3): M110.003590.
Kim W. et al., 2011, Mol Cell. 44 (2): 325-40.

规格：50ug

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