Alpha-2-glycoprotein / AZGP1蛋白产品信息
别名: AZGP1, ZAG, ZNGP1 表达方式: A DNA sequence encoding the human AZGP1 (P25311) (Met1-Ser298) with a C-terminal polyhistidine tag was expressed. 种属: Human 表达宿主: Human Cells Alpha-2-glycoprotein / AZGP1 Protein QC Testing
纯度: > 95 % as determined by SDS-PAGE SDS-PAGE 内**: < 1.0 EU per μg of the protein as determined by the LAL method 稳定性: Samples are stable for up to twelve months from date of receipt at -70℃ 预测N端: Gln 21 分子量: The recombinant human AZGP1 comprises 289 amino acids and has a predicted molecular mass of 33.6 kDa. The apparent molecular mass of the protein is approximately 41 kDa in SDS-PAGE under reducing conditions. 缓冲液: Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. Alpha-2-glycoprotein / AZGP1 Protein Usage Guide
储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. Alpha-2-glycoprotein / AZGP1蛋白背景综述
Alpha-2-glycoprotein, also known as AZGP1, is a member of the MHC class I family. It has been identified as a novel adipokine since it is produced by both white and brown fat adipocytes and may act in a local autocrine fashion in the reduction of adiposity in cachexia. Alpha-2-glycoprotein can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can stimulate lipolysis by adipocytes in vivo and in vitro. Thus it is believed that alpha-2-glycoprotein plays an important role in the regulation of body weight, and age-dependent changes in genetically influenced obesity, and it also regulates melanin production by normal and malignant melanocytes. Alpha-2-glycoprotein may bind polyunsaturated fatty acids. It can cause the extensive fat loss associated with some advanced cancer. 参考文献
Tada T. et al., 1991, J Histochem Cytochem. 39 (9): 1221-6. Vanni H. et al., 2009, Chest. 135 (5): 1197-208. Ueyama H. et al., 1991, Biochem Biophys Res Commun. 177 (2): 696-703. 规格:50ug 关 键 词:Alpha-2-glycoprotein / AZGP1 Protein,实验说明,价格,实验室耗材,生化试剂,上海创赛,博飞美科,实验仪器,厂家
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