GBP-2 / GBP2 Protein| 现货|厂家

GBP-2 / GBP2蛋白产品信息

别名: GBP2
表达方式: 
A DNA sequence encoding the human GBP2 (AAH73163.1) (Met1-Cys588) was expressed with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

GBP-2 / GBP2 Protein QC Testing

纯度: > 90% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Met
分子量: 
The recombinant human GBP2 consists of  599 amino acids and predicts a molecular mass of 68.3 KDa. It migrates as an approximately 62 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

GBP-2 / GBP2 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

GBP-2 / GBP2蛋白背景综述

GBP-2 is a member of the guanylate-binding protein (GBP) family. As GTPases induced by IFN-gamma (Interferon-inducible GTPase), GBPS are key to the protective immunity against microbial and viral pathogens. GBPS are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP-2 is a GTPase that converts GTP to GDP and GMP. It binds GTP, GDP and GMP. GBP-2 hydrolyzes GTP very efficiently. GDP rather than GMP is the major reaction product. GBP-2 is induced by interferons that have antiviral effects and inhibit tumor cell proliferation.

参考文献

Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.
Wistow G. et al., 2002, Mol Vis. 8: 205-20.
Neun R et al., 1996, FEBS Lett. 390 (1): 69-72.

规格：20ug

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