Rat REG3A Protein |技术资料|价格

REG3A蛋白产品信息

别名: REG3A, Pap2, Reg3
表达方式: 
A DNA sequence encoding the rat REG3A(BAA04904.1)(Met1-Gln174) was expressed, fused with a polyhistidine tag at the C-terminus.
种属: Rat
表达宿主: Human Cells

REG3A Protein QC Testing

纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Glu 26
分子量: 
The recombinant rat REG3A comprises 160 amino acids and predicts a molecular mass of 17.9 kDa. The apparent molecular mass of  the recombinant protein is approximately 17 kDa in SDS-PAGE under reducing conditions due to glycosylation.
缓冲液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

REG3A Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

REG3A蛋白背景综述

Regenerating islet-derived protein 3-alpha, also known as Regenerating islet-derived protein III-alpha, REG-3-alpha, REG3A, and HIP, is secreted protein which contains one C-type lectin domain. REG3A is constitutively expressed in intestine. Low expression of REG3A is found in healthy pancreas. It is overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. REG3A is also a stress protein involved in the control of bacterial proliferation. REG3A is down-regulated in most primary human gastric cancer cells, and might be useful in the diagnosis of gastric cancer. Further characterization of the REG3A, should lead to a better understanding of the changes occurring at the molecular level during the development and progression of primary human gastric cancer.

参考文献

Orelle B. et al., 1992, J. Clin. Invest. 90: 2284-2291.
Cavard, C. et al., 2006, Oncogene. 25 (4): 599-608.
Choi, B. et al., 2007, Exp Mol Med. 39 (6): 796-804.
Yasui, W. et al., 2009, Pathol Int. 59 (3): 121-36.

规格：50ug

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