Rat EFNB3 / Ephrin B3 Protein |现货|产品详情

EFNB3 / Ephrin B3蛋白产品信息

别名: EFNB3
表达方式: 
A DNA sequence encoding the rat EFNB3 (NP_001094450) (Met1-Ser224) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
种属: Rat
表达宿主: Human Cells

EFNB3 / Ephrin B3 Protein QC Testing

纯度: (79.6+17)% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Leu 28
分子量: 
The recombinant rat EFNB3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 438 amino acids and has a predicted molecular mass of 48.7 kDa. The apparent molecular mass of the protein is approximately 55 and 34 kDa in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

EFNB3 / Ephrin B3 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

EFNB3 / Ephrin B3蛋白背景综述

Ephrin B3 is a member of the ephrin family. There are two types of ephrins: the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin B3 is a cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin B3 is important in brain development as well as in its maintenance. It is especially important for forebrain function since its expression levels were particularly high in several forebrain subregions compared to other brain subregions.

参考文献

Takemoto M. et al., 2002, Eur J Neurosci. 16 (6): 1168-72.
Brückner K. et al., 1999, Neuron. 22 (3): 511-24.
Bergemann A. et al., 1998, Oncogene. 16 (4): 471-80.

规格:50ug

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