Rat GP1BB Protein|产品详情|价格

GP1BB蛋白产品信息

别名: GP1BB
表达方式: 
A DNA sequence encoding the rat GP1BB (Q9JJM7) (Met1-Cys147) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
种属: Rat
表达宿主: Human Cells

GP1BB Protein QC Testing

纯度: > 85% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Pro 27
分子量: 
The recombinant rat GP1BB/Fc is a disulfide-linked homodimer. The reduced monomer comprises 359 amino acids and has a predicted molecular mass of 40.1 kDa. The apparent molecular mass of the protein is approximately 63 kDa in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

GP1BB Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

GP1BB蛋白背景综述

GP1BB, also known as CD42C, is the beta chain of platelet glycoprotein Ib (GPIb). GPIb is a heterodimeric transmembrane protein. GPIb is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor, and mediates platelet adhesion in the arterial circulation. It consists of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. GPIb alpha chain provides the VWF binding site, and GP1BB contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain.

参考文献

Andrews RK. et al., 1990, Biochemistry. 28 (21): 8317-26.
Clemetson KJ. 2007, Thromb Haemost. 98 (1): 63-8.
Kunishima S. et al., 2003, Int J Hematol. 76 (4): 319-27.

规格：50ug

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