CD36 / GP3B蛋白产品信息
别名: CD36, Q6IMX5
表达方式:
A DNA sequence encoding the rat CD36 (Q66HI4)(Gly30-Lys439) was expressed, fused with a polyhistidine tag at the C-terminus.
种属: Rat
表达宿主: Human Cells
CD36 / GP3B Protein QC Testing
纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Gly 30
分子量:
The recombinant rat CD36 comprises 421 amino acids and predicts a molecular mass of 47.8 kDa. The apparent molecular mass of the recombinant protein is approximately 68 kDa in SDS-PAGE under reducing conditions due to glycosylation.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.
CD36 / GP3B Protein Usage Guide
储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
CD36 / GP3B蛋白背景综述
Platelet glycoprotein 4, also known as Leukocyte differentiation antigen CD36, GPIIIB, GP3B, FAT, and CD36, is integral membrane protein found on the surface of many cell types in vertebrate animals. It belongs to the CD36 family and is found on platelets, erythrocytes, monocytes, differentiated adipocytes, mammary epithelial cells, spleen cells and some skin microdermal endothelial cells. CD36 has also been implicated in hemostasis, thrombosis, malaria, inflammation, lipid metabolism and atherogenesis. CD36 seems to have numerous potential physiological functions. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of plasmodium falciparum parasitized erythrocytes and binds long chain fatty acids. CD36 may also function as a cell adhesion molecule and in the transport and/or as a regulator of fatty acid transport. Defects in CD36 are the cause of platelet glycoprotein IV deficiency also known as CD36 deficiency. As a receptor for thrombospondin 1, CD36 plays a role in the regulation of angiogenesis, which may be a therapeutic strategy for controlling the dissemination of malignant neoplasms.
参考文献
Oquendo P. et al., 1989, Cell. 58 (1): 95-101.
Tandon NN. et al., 1989, J Biol Chem. 264 (13): 7576-83.
Silverstein RL. et al., 1992, J Biol Chem. 267 (23): 16607-12.
Ge Y. et al., 2005, Lab Hematol. 11 (1): 31-7.
规格：50ug
关 键 词：Rat CD36 / GP3B Protein,实验说明,价格，实验室耗材，生化试剂，上海创赛，博飞美科，实验仪器，厂家
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