ROBO2 Protein|ROBO2蛋白质|产品详情|现货

ROBO2蛋白产品信息

别名: ROBO2, KIAA1568
表达方式: 
A DNA sequence encoding the human ROBO2 (Q9HCK4-1) (Met1-Pro859) was expressed with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

ROBO2 Protein QC Testing

纯度: > 95% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Ser 22
分子量: 
The recombinant human ROBO2 consists of  849 amino acids and predicts a molecular mass of 94.2 KDa. It migrates as an approximately 116 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

ROBO2 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

ROBO2蛋白背景综述

ROBO2 is a member of the ROBO family. ROBOs are a group of highly conserved transmembrane glycoproteins that make up a small subgroup of the immunoglobulin (Ig) superfamily. They are best known for their roles as receptors for the Slit family of repellent axon guidance cues. In structure, they are characterized by five C2-type Ig-like repeats, three fibronectin type III domains, a transmembrane region, and an intracellular domain with three (ROBO3) or four (ROBO1, 2) CC (conserved cytoplasmic) motifs. ROBO2 abrogates SLIT-ROBO signaling in vitro. ROBO2 is a receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development.

参考文献

Brose K. et al., 1999, Cell. 96 (6): 795-806.
Brose K. et al., 1999, Neuron. 22 (3): 463-73.
Nagase T. et al., 2001, DNA Res. 7 (4): 273-81.

规格：50ug

关 键 词：ROBO2 Protein,ROBO2蛋白质,产品详情,现货，实验室耗材，生化试剂，上海创赛，博飞美科，实验仪器，厂家

CANSPEC品质提供的ROBO2 Protein|ROBO2蛋白质|产品详情|现货性能**，其优良的品质满足您不同实验的多种需求。

本产品由上海创赛品质提供，欢迎咨询国内免费服务专线：400-608-7598，更多产品信息请登录www.canspecsci.com 或 www.4006087598.com