CALU / Calumenin Protein|价格|参数

CALU / Calumenin蛋白产品信息

别名: CALU
表达方式: 
A DNA sequence encoding the human CALU (O43852-1) (Met1-Arg311) was expressed with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

CALU / Calumenin Protein QC Testing

纯度: > 90% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Lys 20
分子量: 
The recombinant human CALU consists of  303 amino acids and predicts a molecular mass of 35.9 KDa. It migrates as an approximately 46-52 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CALU / Calumenin Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CALU / Calumenin蛋白背景综述

Calumenin is a member of the CREC family. CERC is an acronym for its family members Cab-45, reticulocalbin, Erc-55 (RCN2), and calumenin. Calumenin is a calcium-binding protein localized in the endoplasmic reticulum (ER) and is involved in such ER functions as protein folding and sorting. Calumenin contains 6 EF-hand domains and is expressed in skeletal muscle (at protein level). Calumenin is Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. It seems to inhibit gamma-carboxylase GGCX. Calumenin also binds 7 calcium ions with a low affinity and may modulate calcium release from the sarcoplasmic reticulum.

参考文献

Hartley JL. et al., 2001, Genome Res. 10 (11): 1788-95.
Vorum H. et al., 2000, FEBS Lett. 465 (2-3): 129-34.
Vorum H. et al., 1999, Exp Cell Res. 248 (2): 473-81.

规格：50ug

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