CNPY2 Protein|厂家现货|参数

CNPY2蛋白产品信息

别名: CNPY2, MSAP, TMEM4, ZSIG9
表达方式: 
A DNA sequence encoding the human CNPY2 (Q9Y2B0-1) (Met1-Ser178) was expressed with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

CNPY2 Protein QC Testing

纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Arg 21
分子量: 
The recombinant human CNPY2 consists of  173 amino acids and predicts a molecular mass of 20 KDa. It migrates as an approximately 20 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CNPY2 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CNPY2蛋白背景综述

CNPY2 is a novel MIR-interacting protein. It interacts with the ezrin-radixin-moesin (ERM)-like myosin regulatory light chain-interacting protein, and the two proteins are co-localized in cell lines and in primary neurons. CNPY2 is expressed in different tissues, including brain. Overexpression of CNPY2 enhanced the motility of glioma cells measured in matrigel invasion chambers and using a scratch assay. CNPY2 enhances neurite outgrowth and increases myosin regulatory light chain. It also enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light chain. Inhibition of the corresponding MRLC kinase by ML-7 did not affect migration of CNPY2-overexpressing cells.

参考文献

Trynka G. et al., 2009, Gut. 58 (8): 1078-83.
Danielsen JM. et al., 2011, Mol Cell Proteomics. 10 (3): M110.003590.
Kim W. et al., 2011, Mol Cell. 44 (2): 325-40.

规格：50ug

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