EPHA3 Protein|EPHA3蛋白质|现货|产品详情

EPHA3蛋白产品信息

别名: EPHA3
表达方式: 
A DNA sequence encoding the human EPHA3 (Met1-Gln541) was expressed with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

EPHA3 Protein QC Testing

纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Glu 21
分子量: 
The recombinant human EPHA3 consists of  532 amino acids and predicts a molecular mass of 60.3 KDa. It migrates as an approximately 65-70 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

EPHA3 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

EPHA3蛋白背景综述

EPHA3 gene is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.

参考文献

Holder N. et al., 1999, Development. 126 (10): 2033-44.
Wilkinson DG. 2000, Int Rev Cytol. 196: 177-244.
Xu Q. et al., 2001, Philos Trans R Soc Lond B Biol Sci. 355 (1399): 993-1002.

规格：50ug

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