STC2 / Stanniocalcin 2 Protein |价格|产品详情

STC2 / Stanniocalcin 2蛋白产品信息

别名: STC2
表达方式: 
A DNA sequence encoding the human STC2(O76061) (Met1-Arg302 ) was expressed with the Fc region of human IgG1 at the C-terminus.
种属: Human
表达宿主: Human Cells

STC2 / Stanniocalcin 2 Protein QC Testing

纯度: > 85 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Thr 25
分子量: 
The recombinant human STC2/Fc is a disulfide-linked homodimer. The reduced monomer comprises 519 amino acids and has a predicted molecular mass of 57.7 kDa. The apparent molecular mass of the protein is approximately 63 kDa in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

STC2 / Stanniocalcin 2 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

STC2 / Stanniocalcin 2蛋白背景综述

STC2 has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. It is a secreted, homodimeric glycoprotein which expressed in a wide variety of tissues. STC2 has an anti-hypocalcemic action on calcium and phosphate homeostasis. It may have autocrine or paracrine functions. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. STC2 may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis.

参考文献

Chang AC. et al., 1998, Mol Cell Endocrinol. 141 (1-2): 95-9.
Ishibashi K. et al., 1998, Biochem Biophys Res Commun. 250 (2): 252-8.
Uo CW. et al., 2005, Endocrinology. 146 (1): 469-76.

规格：20ug

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