Rat DCIR / CLEC4A2 Protein|现货|价格

DCIR / CLEC4A2蛋白产品信息

别名: CLEC4A2, Dcir2
表达方式: 
A DNA sequence encoding the rat CLEC4A2 (Q5YIS1) (Gln70-Ser235) was expressed with a polyhistidine tag at the N-terminus.
种属: Rat
表达宿主: Human Cells

DCIR / CLEC4A2 Protein QC Testing

纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: His
分子量: 
The recombinant rat CLEC4A2 comprises 186 amino acids and has a predicted molecular mass of 21.8 kDa. The apparent molecular mass of the protein is approximately 32-36 kDa in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

DCIR / CLEC4A2 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

DCIR / CLEC4A2蛋白背景综述

DCIR, also known as CLEC4A2, is a member of the subfamily of cell surface C-type lectin receptors (CLR), whose multifunctional capacities range from classical Ag uptake and immunoregulatory mechanisms to the involvement in dendritic cell (DC) ontogeny. DCIR acts as an inhibitory receptor depending on its immunoreceptor tyrosine-based inhibitory motif. Expression of mouse DCIR mRNA was observed specifically in spleen and lymph node, slightly increased with dendritic cell maturation during in vitro culture of bone marrow cells, and was not detected in cultured natural killer cells. DCIR deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells.

参考文献

Carninci P. et al., 2005, Science. 309 (5740): 1559-63.
Katayama S. et al., 2005, Science. 309 (5740): 1564-6.
Diez-Roux G. et al., 2011, PLoS Biol. 9 (1): e1000582.

规格：100ug

关 键 词：Rat DCIR / CLEC4A2 Protein,现货,价格，实验室耗材，生化试剂，上海创赛，博飞美科，实验仪器，厂家

CANSPEC品质提供的Rat DCIR / CLEC4A2 Protein|现货|价格性能**，其优良的品质满足您不同实验的多种需求。

本产品由上海创赛品质提供，欢迎咨询国内免费服务专线：400-608-7598，更多产品信息请登录www.canspecsci.com 或 www.4006087598.com