AMIGO2 Protein|技术资料|现货

AMIGO2蛋白产品信息

别名: AMIGO2, ALI1
表达方式: 
A DNA sequence encoding the human AMIGO2 (NP_862830.1) (Met1-Thr398) was expressed with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

AMIGO2 Protein QC Testing

纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Val 40
分子量: 
The recombinant human AMIGO2 consists of  370 amino acids and predicts a molecular mass of 42.3 KDa. It migrates as an approximately 58-63 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

AMIGO2 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

AMIGO2蛋白背景综述

AMIGO2 contains Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. It is a member of the immunoglobulin superfamily, AMIGO family. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. It is required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 is highly expressed in breast, ovary, cervix, and uterus. AMIGO2 may also contribute to signal transduction through its intracellular domain. It may play a role in the tumorigenesis of a subset of gastric adenocarcinomas.

参考文献

Rouhiainen A. et al., 2003, J Cell Biol. 160: 963-73.
Kikkawa Y. et al., 2003, J Neurosci. 23: 5887-96.
Bassi R. et al., 2004, Oncogene. 23: 5056-67.

规格：20ug

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