Mouse CREG / CREG1 Protein|技术资料|价格

CREG / CREG1蛋白产品信息

别名: CREG, Creg1
表达方式: 
A DNA sequence encoding the mouse CREG (O88668) (Met1-Gln220) was expressed with a C-terminal polyhistidine tag.
种属: Mouse
表达宿主: Human Cells

CREG / CREG1 Protein QC Testing

纯度: >95% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Arg 32
分子量: 
The recombinant mouse CREG comprises 200 amino acids and has a predicted molecular mass of 22.9 kDa. The apparent molecular mass of the protein is approximately 28-32 kDa in SDS-PAGE under reducing conditions due to glycosylation.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CREG / CREG1 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CREG / CREG1蛋白背景综述

CREG1 belongs to the CREG family. It is a adenovirus E1A protein which both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Thus it may contribute to the transcriptional control of cell growth and differentiation. The transcriptional control activity of cell growth requires interaction with IGF2R. CREG1 also antagonizes transcriptional activation and cellular transformation by E1A. It shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. CREG1 gene may contribute to the transcriptional control of cell growth and differentiation.

参考文献

Veal E. et al., 2000, Oncogene. 19 (17): 2120-8.
Wen SJ. et al., 2003, Hypertens Res. 25 (4): 647-52.
Grouse LH. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.

规格：20ug

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