Serglycin / SRGN Protein|技术资料|价格

Serglycin / SRGN蛋白产品信息

别名: SRGN, PRG, PRG1
表达方式: 
A DNA sequence encoding the human SRGN (CAA34900.1) (Met1-Leu158) was expressed with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

Serglycin / SRGN Protein QC Testing

纯度: > 95% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Tyr 28
分子量: 
The recombinant human SRGN consists of  142 amino acids and predicts a molecular mass of 16.1 KDa. It migrates as an approximately 57 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

Serglycin / SRGN Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Serglycin / SRGN蛋白背景综述

SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.

参考文献

Hatton MN. et al., 1985, Biochem J. 230 (3): 817-20.
Schick BP. et al., 1995, J Cell Physiol. 165 (1): 96-106.
Kato S. et al., 1995, Gene. 150 (2): 243-50.

规格:50ug

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