Rat MBL1 Protein|技术资料|厂家现货

MBL1蛋白产品信息

别名: MBL1
表达方式: 
A DNA sequence encoding the rat MBL1 (P19999) (Met1-Ala238) was expressed with the Fc region of human IgG1 at the C-terminus.
种属: Rat
表达宿主: Human Cells

MBL1 Protein QC Testing

纯度: > 85% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Ser 18
分子量: 
The recombinant rat MBL1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 462 amino acids and has a predicted molecular mass of 50.5 kDa. The apparent molecular mass of the protein is approximately 56 kDa in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

MBL1 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

MBL1蛋白背景综述

Mannose binding lectin (MBL), also named mannose or mannan-binding protein (MBP), belongs to the class of collectins in the C-type lectin superfamily. Its function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL recognizes carbohydrate patterns found on the surface of a large number of pathogenic micro-organisms including bacteria, viruses, protozoa and fungi. Binding of MBL to a micro-organism results in activation of the lectin pathway of the complement system. Two forms of MBL, MBL-A and MBL-C, were characterized in rodents, rabbits, bovine and rhesus monkeys, whereas only one form was identified in humans, chimpanzees and chickens. The two forms are encoded by two distinct genes named MBL1 and MBL2, which have been identified in many species. Mouse MBL1, also known as MBL-A , contains one C-type lectin domain and one collagen-like domain, and is located intracellular, most predominantly in the rough endoplasmic reticulum.

参考文献

Sastry R. et al., 1995, Mamm Genome. 6 (2): 103-110.
Lillie B. N. et al., 2006, Immunogenetics. 58 (12): 983-993.
Phatsara C. et al., 2007, Int J Immunogenet. 34 (1): 55-63.

规格：50ug

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