NRN1L / Cpg15-2 / Neuritin 1-like Protein|价格|参数

NRN1L / Cpg15-2 / Neuritin 1-like蛋白产品信息

别名: NRN1L
表达方式: 
A DNA sequence encoding the human NRN1L (Q496H8) (Met1-Thr138) was expressed with the Fc region of mouse IgG1 at the C-terminus.
种属: Human
表达宿主: Human Cells

NRN1L / Cpg15-2 / Neuritin 1-like Protein QC Testing

纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Ala 36
分子量: 
The recombinant human NRN1L/mFc  comprises 337 amino acids and has a predicted molecular mass of 37.6 kDa. The apparent molecular mass of the monomer is approximately 38 kDa in SDS-PAGE under reducing conditions due to glycosylation.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

NRN1L / Cpg15-2 / Neuritin 1-like Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

NRN1L / Cpg15-2 / Neuritin 1-like蛋白背景综述

NRN1L, also known as neuritin 1-like and Cpg15-2, belongs to the neuritin family. Neuritin is a GPI-anchored protein that promotes neurite outgrowth and branching of neuritic processes in primary hippocampal and cortical cells. Neuritin expression also enhances the development of motor neuron axon arbors by promoting neuromuscular synaptogenesis and by stimulating the addition of new axon branches. Neuritin is induced by neuronal activity and by the neurotrophins, BDNF and NT3. NRN1L contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. In vitro assays demonstrated that NRN1L promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis.

参考文献

Strausberg RL. et al., 2002, Proc Natl Acad Sci. 99 (26): 16899-903.
Clark HF. et al., 2003, Genome Res. 13 (10): 2265-70.
Fujino T. et al., 2008, J Comp Neurol. 507 (5): 1831-45.

规格：50ug

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