Cynomolgus LAMP2 Protein|技术资料|报价

LAMP2蛋白产品信息

别名: LAMP2
表达方式: 
A DNA sequence encoding the cynomolgus LAMP2 (G7Q3L7) (Leu29-Phe376) was expressed with a polyhistidine tag at the C-terminus.
种属: Cynomolgus
表达宿主: Human Cells

LAMP2 Protein QC Testing

纯度: > 85 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Leu 29
分子量: 
The recombinant cynomolgus LAMP2 comprises 359 amino acids and has a calculated molecular mass of 39.8 KDa. The apparent molecular mass of it is approximately 64-68 KDa respectively in SDS-PAGE.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

LAMP2 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

LAMP2蛋白背景综述

Lysosomal-associated membrane protein 2 (LAMP2) also known as CD107b (Cluster of Differentiation 107b), which is clinically characterized by cardiomyopathy, myopathy, and variable mental retardation. The pathological hallmark of the disease is the absence of LAMP-2 immunohistochemical staining in muscle. The LAMP-2 gene mutations reported thus far are generally private mutations. LAMP2/CD107b is a member of a family of membrane glycoproteins, and plays a role in tumor cell metastasis. Additionally, LAMP2/CD107b is associated with Danon disease.

参考文献

Bertini E. et al., 2005, Neuropediatrics. 36 (5): 309-13.
Di Blasi C. et al., 2008, Neuromuscul Disord. 18 (12): 962-6.

规格：50ug

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