Cynomolgus TFRC / Transferrin Receptor Protein|厂家现货|价格

TFRC / Transferrin Receptor蛋白产品信息

别名: TFRC, Tfrc
表达方式: 
A DNA sequence encoding the cynomolgus TFRC (NP_001244232.1) (Cys89-Phe760) was expressed with a polyhistidine tag at the N-terminus.
种属: Cynomolgus
表达宿主: Human Cells

TFRC / Transferrin Receptor Protein QC Testing

纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: His
分子量: 
The recombinant cynomolgus TFRC comprises 692 amino acids and has a calculated molecular mass of 77.6 KDa. The apparent molecular mass of it is approximately 65-85 KDa  in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

TFRC / Transferrin Receptor Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

TFRC / Transferrin Receptor蛋白背景综述

Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p90, CD71 and TFRC, is a single-pass type II membrane protein which belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in  UIOP[] the pancreas that could be applied as potential diagnostic and therapeutic target.

参考文献

Douabin-Gicquel V. et al., 2001, Hum Genet. 109: 393-401.
Ryschich E. et al., 2004, Eur J Cancer. 40 (9): 1418-22.
Tosoni D. et al., 2005, Cell. 123: 875-88.
Wollscheid B. et al., 2009, Nat Biotechnol. 27: 378-86.

规格：50ug

关 键 词：Cynomolgus TFRC / Transferrin Receptor Protein,厂家现货,价格，实验室耗材，生化试剂，上海创赛，博飞美科，实验仪器，厂家

CANSPEC品质提供的Cynomolgus TFRC / Transferrin Receptor Protein|厂家现货|价格性能**，其优良的品质满足您不同实验的多种需求。

本产品由上海创赛品质提供，欢迎咨询国内免费服务专线：400-608-7598，更多产品信息请登录www.canspecsci.com 或 www.4006087598.com