FAM3C / ILEI Protein|FAM3C / ILEI蛋白质|技术资料|现货

FAM3C / ILEI蛋白产品信息

别名: FAM3C, ILEI
表达方式: 
A DNA sequence encoding the human FAM3C (Q92520)(Met1-Asp227) was expressed with the Fc region of human IgG1 at the C-terminus.
种属: Human
表达宿主: Human Cells
FAM3C / ILEI Protein QC Testing

纯度: (73.6+19.1)% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Gln 25
分子量: 
The recombinant human FAM3C/Fc is a disulfide-linked homodimer. The reduced monomer comprises 444 amino acids and has a predicted molecular mass of 49.2 kDa. The apparent molecular mass of the protein is approximately 53 and 35 kDa in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

FAM3C / ILEI Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

FAM3C / ILEI蛋白背景综述

FAM3C, also known as ILEI, is a member of the FAM3 family. It can be detected in resent in most secretory epithelia. FAM3C may be involved in retinal laminar formation. It promotes epithelial to mesenchymal transition. A change in expression of FAM3C has been noted in pancreatic cancer-derived cells. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer.

参考文献

Zhu Y. et al., 2002, Genomics. 80 (2): 144-50.
Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.
Quéméner-Redon S. et al., 2003, Nature. 424 (6945): 157-64.

规格：50ug

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