CD81 / TAPA-1 Protein|价格|厂家|技术资料

CD81 / TAPA-1蛋白产品信息

别名: CD81, TAPA1, TSPAN28
表达方式: 
A DNA sequence encoding the human CD81 (NP_004347.1) (Phe113-Lys201) was expressed with the Fc region of mouse IgG1 at the N-terminus.
种属: Human
表达宿主: Human Cells

CD81 / TAPA-1 Protein QC Testing

纯度: (94.0%+4.4)% as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Asp
分子量: 
The recombinant human CD81/mFc  comprises 325 amino acids and has a predicted molecular mass of 36.4 kDa. The apparent molecular mass of the monomer is approximately 38-42 kDa in SDS-PAGE under reducing conditions due to glycosylation.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CD81 / TAPA-1 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CD81 / TAPA-1蛋白背景综述

CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.

参考文献

Petracca R. et al., 2000, J Virol. 74 (10): 4824-30.
Bartosch B. et al., 2003, The Journal of Biological Chemistry. 278 (43): 41624-30.
Clark KL. et al., 2001, Journal of Immunology. 167 (9): 5115-21.

规格：50ug

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