CART / CARTPT Protein|使用说明|厂家现货

CART / CARTPT蛋白产品信息

别名: CARTPT, CART
表达方式: 
A DNA sequence encoding the human CARTPT (NP_004282.1) (Met1-Leu116) was expressed with the Fc region of mouse IgG1 at the C-terminus.
种属: Human
表达宿主: Human Cells

CART / CARTPT Protein QC Testing

纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Gln 28
分子量: 
The recombinant human CARTPT/mFc  comprises 323 amino acids and has a predicted molecular mass of 36.3 kDa. The apparent molecular mass of the monomer is approximately 37 kDa in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CART / CARTPT Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CART / CARTPT蛋白背景综述

CART, also known as CARTPT, belongs to the CART family. CART plays a critical role in appetite suppression, cell survival, thermoregulation, glucose sensing, stimulation of hormone secretion, as well as for the regulatory function of the islets of Langerhans. CART is a satiety factor closely associated with the actions of leptin and neuropeptide Y. It also functions as a anorectic peptide which inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. CART promotes neuronal development and survival in vitro.

参考文献

Landerholm K. et al., 2012, Clin Cancer Res. 18 (13): 3668-76.
Kasacka I. et al., 2012, Acta Histochem. 114 (7): 695-9.
Zhang J. et al., 2012, J Biol Chem. 287 (51): 42574-87.

规格：20ug

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